Osteoporosis in diet are at the highest risk

Osteoporosis (OP)
is a silently progressing metabolic bone disease. It is estimated to affect 200
million women worldwide – approximately one-tenth of women aged 60, one-fifth
of women aged 70, two-fifths of women aged 80 and two-thirds of women aged 90 1.
It is widely prevalent in Indian population as well 2. OP leads to loss of
bone mass resulting in fractures after minor trauma, especially of spinal vertebrae,
the bones of the forearm
and hip. Globally, more than 8.9 million fractures every year occurs secondary
to OP 3 and a considerable cause of morbidity and mortality 4.

 

Studies have shown
that post menopausal women with a positive family history, and who have low
intake of calcium and Vitamin D in diet are at the highest risk 5. There is
exaggerated bone loss as compared to new bone formation in OP. Therefore, measures
most commonly applied for OP management are- regular weight bearing exercises, oral
calcium and Vitamin D (Cholecalciferol) supplementation and drugs that decrease
osteoclastic bone resorption like bisphosphonates (risedronate, alendronate), Selective
Estrogen Receptor Modulators (Raloxifene) and Calcitonin 6. Teriperatide, a
congener of parathyroid hormone has been recently introduced for OP treatment
and it has been shown to increase new bone formation 7. However, much less is
known about the effectiveness of Teriperatide considering its high cost in the Indian
population.

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Despite
availability of various treatments for OP it has a profound negative impact on
the Quality of Life (QoL) as pointed out by numerous studies 8. Fractures
have a negative impact on self-esteem, body image, and mood, which may lead to
psychological consequences. Thus, the psychosocial suffering of the patient must
also be evaluated. Furthermore, there is a paucity of Indian studies in this
field. Hence the QoL evaluation of post menopausal patients suffering from OP becomes
imperative.

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